Jingquan Liu is a professor in Qingdao University. He received his bachelor from Shandong University in 1989. His master and PhD were obtained from the University of New South Wales (UNSW) in 1999 and 2004 respectively, where his PhD was undertaken under the guidance of Prof. Justin Gooding. In 2004 he worked as a CSIRO-UTS post-doctoral fellow prior to returning to UNSW with Prof. Tom Davis as a Vice-Chancellor’s Research Fellow in 2006. In 2010 he took up a professorship at Qingdao University.
His research interests focus on the application and commercialization of graphene, controlled living radical polymerization of versatile polymeric architectures and various bio- and nano-composites. He has co-authored over 90 peer-reviewed research papers and 3 book chapters. He was employed as a Taishan Scholar in 2010 and obtained the Qingdao Outstanding Contribution Award in 2013.
演讲题目：Applications of Graphene in Drug Delivery and Sensing Technology
内容摘要
Graphene’s unique structural elements, including being a single-atom thick, two-dimensional and extensively conjugated, endow graphene with advantageous biocompatibility and thermal, electric and mechanical properties, which enhance its potential for application in drug delivery[1,2] and the preparation of ultrasensitive sensors. [3-5] In this presentation, we report the preparation of a pH-sensitive graphene/poly (acrylic acid) hydrogel in situ RAFT polymerization for controlled drug release (Fig.1).[1] The preparation of biodegradable and positively charged graphene/poly(2-(dimethylamino) ethylacrylate) nanocomposite for DNA uptake and release is also presented.[2] Gold electrode can also be modifided with graphene via non-covalent interaction for the analysis of heavy metals.[3] The as-prepared electrodes exhibited high detection sensitivity with the lowest detection limit of 1.5 nM for Cu2+ and 0.4 nM for Pb2+ solutions, respectively. Furthermore, when glucose oxidase (GOx) was modified with surface-bound pyrene functionalities it can be self-assembled onto graphene nanosheets via non–covalent π–π stacking interaction to afford multi-layered enzyme electrode with a broad lineardetection limit of 0.2 to 40 mM and sensitivity.[4] In addition, highly oriented pyrolytic graphite (HOPG) electrodes modified with pyrene functionalised biotin (PFB) via π−π stacking and ethylene glycol anti−fouling molecules via covalent bonding for streptavidin analysis is also presented. The as−prepared biotinylated electrode was used as the sensing probe to analyze the concentration of streptavidin via the electrochemistry diminution resulted from the desorption rate of pyrene modified biotin mediated by biotin−streptavidin recognition (Fig.2).
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